Close
Date TimeSeptember 19, 2019
VoiceA common antidepressant does little to relieve symptoms of depression, according to the biggest study of its kind – but it is effective at improving anxiety.
Common Antidepressant, Sertraline, Does Little To Relieve Depression
The study found that most people taking sertraline saw little or no effect on depressive symptoms – such as low mood, lack of interest in things and poor sleep – in the first six to 12 weeks of taking the drug.
However, sertraline did cut symptoms of anxiety – such as worrying and feeling nervous or restless – and people were twice as likely to say their overall mental health had improved. 
Experts said they were “surprised” by the findings relating to depression, but it was clear the drugs helped cut anxiety and should continue to be prescribed by GPs. READ MORE: Antidepressant Prescriptions Have Doubled In A Decade – Could This Be Why? The study, published in the journal the Lancet Psychiatry and led by University College London (UCL) researchers, was conducted in GP surgeries across England. It included 653 people aged 18 to 74 with mild to moderate symptoms of depression, for whom there was clinical uncertainty over whether they needed treatment. They were split into two groups.
The first group was given a dummy drug for 12 weeks while the second group was given sertraline. The results showed depressive symptoms were 5% lower after six weeks in the sertraline group, which was “no convincing evidence” of an effect. After 12 weeks, there was a 13% reduction – a finding the experts described as “weak”.
But the drug did offer clear benefits on reducing anxiety, with a 21% reduction in symptoms at six weeks and 23% at 12 weeks. People on sertraline were twice as likely to say they felt better after the trial. 
Professor Glyn Lewis, head of division at UCL Psychiatry, who led the study, said: “Antidepressants work but perhaps in a different way to the way we had originally thought. They seem to be working on anxiety symptoms first before any smaller, and later, possible effects on depression.
“We definitely need better treatments for depression – we need more research in this area. This is an unexpected result. Our primary hypothesis was that it would affect those depressive symptoms at six weeks and we didn’t find that. So it is an unexpected finding.”
The researchers said people with depression often also have symptoms of anxiety – something the drug offered clear benefits for. “It would be unusual for somebody with depression or depressive symptoms not to be experiencing several other symptoms of anxiety,” said Dr Gemma Lewis, from UCL. 
“It appears that people taking the drug are feeling less anxious, so they feel better overall, even if their depressive symptoms were less affected.
“We hope that we have cast new light on how antidepressants work, as they may be primarily affecting anxiety symptoms such as nervousness, worry and tension, and taking longer to affect depressive symptoms.”READ MORE: How To Come Off Your Antidepressants Safely – Tips From Mental Health Experts The study, funded by the National Institute for Health Research (NIHR), is the largest placebo-controlled trial of an antidepressant that has not been funded by the pharmaceutical industry. 
Commenting on the findings, Professor Helen Stokes-Lampard, chairwoman of the Royal College of GPs, said: “It is well-established that it often takes a while for patients to feel the full benefits of modern antidepressants and that they work best when taken for significant periods of time, which is one reason why doctors will often review patients after several weeks of use and then prescribe a fairly long course of the drugs, if they appear to be beneficial.
“This study gives an interesting insight into how a medication primarily used to treat depression may be improving a patient’s health in other ways in the shorter term, by reducing symptoms of anxiety, which is often associated with depression.”
Dr Sameer Jauhar, a senior research fellow and consultant psychiatrist in the NHS, said: “The findings that anxiety symptoms, though not depressive symptoms, improved relatively quickly, and that people felt better taking these medicines, probably reflects why GP do prescribe them.
“It is not surprising that depressive symptoms did not improve to a great extent, given that only around half the people had a diagnosis of depression.”
Between 2017 and 2018, 7.3 million people were prescribed antidepressants in England – 17% of the population. Sertraline is a selective serotonin reuptake inhibitor (SSRI), the most common class of antidepressant.READ MORE: What’s Really Going On With Brexit Medicine Shortages? It's 'Complicated' I Have Three Mental Health Diagnoses. This Is How I Live With Them. Here's How Grapefruit Juice Might Be Interfering With Your Medication

Related Stories
England’s Owen Farrell ‘missing part of his nose’ after bruising win over USAEngland’s Owen Farrell ‘missing part of his nose’ after bruising win over USA
Investigation Launched Into Awarding Of Grant To Boris Johnsons Close FriendInvestigation Launched Into Awarding Of Grant To Boris Johnson's 'Close Friend'
Wales v Ireland: Rugby World Cup warm-up – live!Wales v Ireland: Rugby World Cup warm-up – live!
Labour NEC In Shock Move To Abolish Tom Watsons Deputy Leader PostLabour NEC In Shock Move To Abolish Tom Watson's Deputy Leader Post
George Ford makes England’s World Cup attack hum and cannot be dropped   | Nick EvansGeorge Ford makes England’s World Cup attack hum and cannot be dropped | Nick Evans
Bill Clinton and Jeb Bush seek refuge from Trump impeachment stormBill Clinton and Jeb Bush seek refuge from Trump impeachment storm
Anthony Joshua defends desert fight and points to Saudi Arabia ‘reforms’Anthony Joshua defends desert fight and points to Saudi Arabia ‘reforms’
Philip Hammond Says He Will Not Back Election As Brexit Crisis LoomsPhilip Hammond Says He Will Not Back Election As Brexit Crisis Looms
Man with no shame: the papers on Boris Johnsons performance in the Commons'Man with no shame': the papers on Boris Johnson's performance in the Commons
Rugby World Cup: England v France off and Japan v Scotland under threat from Typhoon HagibisRugby World Cup: England v France off and Japan v Scotland under threat from Typhoon Hagibis
Latest News
From Charlie Chaplin to Jojo Rabbit: an unlikely history of Nazi comediesFrom Charlie Chaplin to Jojo Rabbit: an unlikely history of Nazi comedies
British Holidaymakers Detained After Accidentally Crossing The US BorderBritish Holidaymakers Detained After 'Accidentally' Crossing The US Border
What Happens Next? Boris Johnson’s Possible Brexit Outcomes, ExplainedWhat Happens Next? Boris Johnson’s Possible Brexit Outcomes, Explained
EastEnders Airs Accidental Set  Blunder – And It Hasnt Gone Unnoticed By FansEastEnders Airs Accidental Set Blunder – And It Hasn't Gone Unnoticed By Fans
Andi Peters Does His Best To Distract From Piers Morgan Drama With Hilarious Good Morning Britain FallAndi Peters Does His Best To Distract From Piers Morgan Drama With Hilarious Good Morning Britain Fall
Four Football Fans In Bulgaria Detained After Racist Abuse In England MatchFour Football Fans In Bulgaria Detained After Racist Abuse In England Match
Lewis Hamilton Says Going Vegan Is Only Way To Save The Planet – People Have ThoughtsLewis Hamilton Says Going Vegan Is 'Only Way To Save The Planet' – People Have Thoughts
The 2019 Liberty London Beauty Advent Calendar Has An Impressive Line-Up Of GoodiesThe 2019 Liberty London Beauty Advent Calendar Has An Impressive Line-Up Of Goodies
The Latest: Kremlin recognizes Turkeys right to securityThe Latest: Kremlin recognizes Turkey's right to 'security'
Just a matter of time before president removed following impeachment testimony: Former Trump aide'Just a matter of time' before president removed following impeachment testimony: Former Trump aide
Leaders
Donald-TrumpDonald Trump
45th President of the United States of America
Mike-PenceMike Pence
Vice President of the United States
Boris-JohnsonBoris Johnson
British Prime Minister
Angela-MerkelAngela Merkel
Chancellor of Germany
Emmanuel-MacronEmmanuel Macron
President of France
Justin-TrudeauJustin Trudeau
Prime Minister of Canada
Nancy-PelosiNancy Pelosi
Speaker of the United States House of Representatives
Barack-ObamaBarack Obama
44th U.S. President
Theresa-MayTheresa May
Member of Parliament of the United Kingdom
Vladimir-PutinVladimir Putin
Russian President
Shinzo-AbeShinzō Abe
Prime Minister of Japan
Related Stories
England’s Owen Farrell ‘missing part of his nose’ after bruising win over USAEngland’s Owen Farrell ‘missing part of his nose’ after bruising win over USA
Investigation Launched Into Awarding Of Grant To Boris Johnsons Close FriendInvestigation Launched Into Awarding Of Grant To Boris Johnson's 'Close Friend'
Wales v Ireland: Rugby World Cup warm-up – live!Wales v Ireland: Rugby World Cup warm-up – live!
Labour NEC In Shock Move To Abolish Tom Watsons Deputy Leader PostLabour NEC In Shock Move To Abolish Tom Watson's Deputy Leader Post
George Ford makes England’s World Cup attack hum and cannot be dropped   | Nick EvansGeorge Ford makes England’s World Cup attack hum and cannot be dropped | Nick Evans
Bill Clinton and Jeb Bush seek refuge from Trump impeachment stormBill Clinton and Jeb Bush seek refuge from Trump impeachment storm
Anthony Joshua defends desert fight and points to Saudi Arabia ‘reforms’Anthony Joshua defends desert fight and points to Saudi Arabia ‘reforms’
Philip Hammond Says He Will Not Back Election As Brexit Crisis LoomsPhilip Hammond Says He Will Not Back Election As Brexit Crisis Looms
Man with no shame: the papers on Boris Johnsons performance in the Commons'Man with no shame': the papers on Boris Johnson's performance in the Commons
Rugby World Cup: England v France off and Japan v Scotland under threat from Typhoon HagibisRugby World Cup: England v France off and Japan v Scotland under threat from Typhoon Hagibis
Latest News
From Charlie Chaplin to Jojo Rabbit: an unlikely history of Nazi comediesFrom Charlie Chaplin to Jojo Rabbit: an unlikely history of Nazi comedies
British Holidaymakers Detained After Accidentally Crossing The US BorderBritish Holidaymakers Detained After 'Accidentally' Crossing The US Border
What Happens Next? Boris Johnson’s Possible Brexit Outcomes, ExplainedWhat Happens Next? Boris Johnson’s Possible Brexit Outcomes, Explained
EastEnders Airs Accidental Set  Blunder – And It Hasnt Gone Unnoticed By FansEastEnders Airs Accidental Set Blunder – And It Hasn't Gone Unnoticed By Fans
Andi Peters Does His Best To Distract From Piers Morgan Drama With Hilarious Good Morning Britain FallAndi Peters Does His Best To Distract From Piers Morgan Drama With Hilarious Good Morning Britain Fall
Four Football Fans In Bulgaria Detained After Racist Abuse In England MatchFour Football Fans In Bulgaria Detained After Racist Abuse In England Match
Lewis Hamilton Says Going Vegan Is Only Way To Save The Planet – People Have ThoughtsLewis Hamilton Says Going Vegan Is 'Only Way To Save The Planet' – People Have Thoughts
The 2019 Liberty London Beauty Advent Calendar Has An Impressive Line-Up Of GoodiesThe 2019 Liberty London Beauty Advent Calendar Has An Impressive Line-Up Of Goodies
The Latest: Kremlin recognizes Turkeys right to securityThe Latest: Kremlin recognizes Turkey's right to 'security'
Just a matter of time before president removed following impeachment testimony: Former Trump aide'Just a matter of time' before president removed following impeachment testimony: Former Trump aide
Leaders
Donald-TrumpDonald Trump
45th President of the United States of America
Mike-PenceMike Pence
Vice President of the United States
Boris-JohnsonBoris Johnson
British Prime Minister
Angela-MerkelAngela Merkel
Chancellor of Germany
Emmanuel-MacronEmmanuel Macron
President of France
Justin-TrudeauJustin Trudeau
Prime Minister of Canada
Nancy-PelosiNancy Pelosi
Speaker of the United States House of Representatives
Barack-ObamaBarack Obama
44th U.S. President
Theresa-MayTheresa May
Member of Parliament of the United Kingdom
Vladimir-PutinVladimir Putin
Russian President
Shinzo-AbeShinzō Abe
Prime Minister of Japan
PHOTOS: Rescued sea otter pups being named in a digital contest
U.S. drone strike kills 30 pine nut farm workers in Afghanistan
CNN Brings on Corey Lewandowski, a Known Liar, for Totally Batshit Interview
How dangerous is vaping? The science remains hazy
Donald Trump dismisses reports of 'promise' to foreign leader triggering intel whistleblower
From DNA, scientists create skull of Neanderthal cousin
US faces ‘unacceptable risk’ of exploding planes and crumbling buildings if Trump border wall funds not replaced, Pentagon warns
Bernie Sanders First to Reach 1 Million Donors: Campaign Update
Transgender prisoner who sued dies days before release
Mercury prize 2019: rapper Dave wins for 'exceptional' Psychodrama
Mercury prize 2019: Dave wins for Psychodrama, plus all the action as it happened
Mason Greenwood’s first Manchester United goal earns win over Astana
England’s Billy Vunipola ready to follow in family footsteps at World Cup
Rob Howley faces uncertain future with long wait for betting verdict
Mata’utia makes the difference as Castleford upset Warrington in play-off
Age not an obstacle in Serena Williams' pursuit of 24th major, Mouratoglou says
Eddie Jones looks to cash in on England’s World Cup campaign in Japan
Wolves make poor start to group stage as Braga exploit sloppy defending
Ryan Christie penalty secures draw for Celtic at Rennes despite late red card
Europa League: Karius drops clanger in Besiktas defeat, Dudelange shock Apoel
Justin Trudeau Says He Can’t Remember How Many Times He’s Worn Blackface
Netanyahu, Gantz in standoff over Israeli unity government
Mountain lion wanders into couple's home while they watch TV before getting itself locked in bathroom
Just How Good Is the Impossible Burger for You or the Planet?
Prosecutors: 2 Chicago gangbangers executed 9-year-old boy in revenge killing against his father's rival gang
Florida man held without bond in deaths of wife, 4 children
Taylor Swift: 'White supremacy is repulsive. There is nothing worse'
Manchester United v Astana, Wolves v Braga, Rangers v Feyenoord – live!
All the world’s a stage as giants of the game prepare for an epic battle | Robert Kitson
Bukayo Saka inspires Arsenal to thrilling win at Eintracht Frankfurt
Sheffield United’s Prince Abdullah defends Bin Ladens over club links
Justin Trudeau says he doesn't want to be 'definitive' about how many times he wore racist makeup
Judge Sides With Michael Jackson Estate in ‘Leaving Neverland’ Dispute
E-Cigarette Brands Spent $57 Million on TV Ads This Year, Including 54% to Networks That Now Reject Them
Chelsea Handler says Trump is the 'perfect example of white privilege': 'It's nauseating'
How a White Nationalist Mass Shooting Inspired Janet Jackson’s Masterpiece
Death of troubled officer whose gun wasn't taken away marks record number of suicides in NYPD
‘We are preparing for the worst’: Storm Area 51 event could be disaster, locals fear
American Airlines Mechanic who Sabotaged Plane before Takeoff Suspected of ISIS Ties
Border closure leaves rice-loving Nigerians steaming
US drone strike 'kills 30 Afghan farmers'
Parole board weighs release of woman in texting suicide case
Lorena makes landfall in southwest Mexico as Category 1 force hurricane
Dem Senator Dismisses O’Rourke’s Gun-Confiscation Plan: ‘Beto’s Not Taking My Guns Away from Me’
Apple’s iPhone 11 Pro has one-third as much RAM as top Android flagships, but it still crushes them
Ex-lover in corn rake killing: Woman was afraid of husband
U.S. to return about $100 million to the Treasury for an Afghanistan project due to a lack of transparency
Parents of Israeli held in Gaza plead for news, action five years on
Mercury prize 2019: follow the ceremony live!
Eintracht Frankfurt 0-3 Arsenal, Rennes 1-1 Celtic: Europa League – live!
Lewis Hamilton ‘down for some hard racing’ in Singapore after Leclerc clash
Callum Hudson-Odoi commits to Chelsea with new five-year contract
PGA Championship: Matt Wallace takes first-day lead as Rory McIlroy struggles
Nike ends deal with Antonio Brown amid sexual assault allegations
County cricket: Kent thrash Yorkshire, Lancashire beat Middlesex – as it happened
Wallabies enter Rugby World Cup with consistency under scrutiny | Bret Harris
Adam Schiff slams 'unprecedented' decision to withhold whistleblower complaint from Congress
Chelsea Handler says Trump is the 'perfect example of white privilege': ‘It’s nauseating’
Meghan Markle and Prince Harry Travel to Rome for Friend Misha Nonoo's Wedding
UK Weather Forecast: Lovely Sun This Weekend Then It's Autumn Proper
Why I Won't Celebrate My Breastfeeding Journey On Social Media
Nevada Desert Towns Prep for Possible 'Storm Area 51' Influx
Free Nazanin: EU Parliament reiterates demand for Nazanin Zaghari's unconditional release in Iran and condemns treatment of activists
BBC to move more staff and services out of London
iOS 13 download: New iPhone software update will include bugs and have missing features
The Latest: Czech company: Our engine wasn't used in attack
Netanyahu calls on Gantz to form a unity government together
Women’s March Dismisses New Board Member amid Backlash over Statements Comparing ISIS to U.S. Military
'Serial killer' charged with killing four women and leaving their bodies in abandoned houses
Justin Trudeau blackface: details emerge of third incident
'It's bad': Hundreds of water rescues as Imelda soaks Texas
Parents of Israeli held in Gaza plea for news, action five years on
Netanyahu Lost. His Enemies Won. But Who Can Govern Israel?
Jerry becomes Category 1 hurricane swirling in Atlantic
Pop's need for speed: 'You have to drop new stuff constantly'
Eintracht Frankfurt v Arsenal, Rennes v Celtic: Europa League – live!
County cricket: Kent thrash Yorkshire, Lancashire beat Middlesex by 104 runs – live!
Netflix considering paying out bonuses for successful films
Far-Right Extremism Is Britain's Fastest Growing Terror Threat, Police Say
Outnumbered's Claire Skinner Addresses 'Lovely' Hugh Skinner Romance
Here's What Happened On The Final Day Of The Supreme Court Prorogation Hearing
Charges Dropped Against Man Accused Of Murdering PC Andrew Harper
Intel IG testifies on whistleblower complaint of Trump making 'promise' to foreign leader
Black panther found roaming French rooftops
Newsmaker: The anti-Netanyahu? Ex-general Gantz poised for top office
'It's bad': Water rescues begin as Imelda soaks east Texas
2020 Vision Thursday: Why Kamala Harris is struggling in the polls
Ralph Nadler: Corey Lewandowski obligated to answer questions
Solar panels, vegan diets, no flights: meet America's climate revolutionaries
Third Photo of Justin Trudeau in Blackface Threatens to Destroy His Progressive Reputation
Speed bumps on German road to fight climate change
Report: Cleanup of abandoned oil, gas wells could cost US
Taliban Kills 20 in Third Day of Surging Violence in Afghanistan
Peter Beardsley barred from football for seven months over racist language
Spectacle of Singapore offers F1’s best chance of attracting a new audience | Giles Richards
The return of the Champions League – Football Weekly Extra
Rugby World Cup: fans give their previews and predictions
The Fiver | Talk of crisis is relative. Then again, this is Real Madrid
Trump on whether Jerome Powell's job is safe: 'Sure, why not?'
Rambo: Last Blood review – Stallone storms Mexico in a laughable Trumpian fantasy
Aardman's 20 best films – ranked!
PC Andrew Harper Death: Murder Charge Dropped Against Jed Foster
Man 'Conspired With Lottery Employee To Fake His Way To £2.5m Jackpot'
Met Police Places Restrictions On Climate Strike In London
Another Justin Trudeau Blackface Video Reported After Apology For Brownface Photo
Women Can Now Buy A Pillow To 'Fight Cleavage Wrinkles', Because Apparently That's A Thing
Buckingham Palace Is Annoyed At David Cameron's Current Memoirs Promo Tour
Pete Buttigieg Rolls Out Health-Care Plan: Campaign Update
Migrants say they face danger before court in Texas tents
Trump tells reporters border wall is ‘wired’, immediately after army general asks him not to discuss in public
Jimmy Carter says he hopes 'there's an age limit' for presidency in apparent jab at Joe Biden, Bernie Sanders
My life of WhatsApp and existential crises in the world of amateur football | Max Rushden
Rugby World Cup 2019 stadium guide
County cricket: Kent beat Yorkshire by 433 runs, Lancashire v Middlesex – live!
Rugby World Cup 2019: a guide to the referees
Kieran Trippier delivering for Atlético Madrid and relishing new 100mph life | Sid Lowe
Shola Amoo: the man behind the British Moonlight
‘Farmed’ out to a white family, I became a skinhead: Adewale Akinnuoye-Agbaje on his first film
Gillian Anderson: ‘I fall in love with my characters’
As HIV Testing Rates Rise Thanks To Gareth Thomas, Here Are 5 Myths That Still Need Busting
Class A Drug Use In The UK Is At Record Highs
Liam Payne Recalls Secret Feud With Fellow One Direction Star Louis Tomlinson
Piers Morgan Names His Price After Ant And Dec's Claim He 'Keeps Wriggling Out Of' Im A Celebrity Stint
Playing Truant Can Be A Mark Of Anxiety in Children – Here Are The Signs
This Activist Invited ICE to a Community Meeting. Days Later They Arrested Him
South Korea serial killer suspect identified after 33 years
Russia's Kaliningrad Territory Is Armed to The Teeth. NATO Wants to Crush It in a War
Trump news - live: Impeachment hearing exposes 'absolute coverup by White House', as former top aide dodges questions
Liam Gallagher: Why Me? Why Not review | Alexis Petridis's album of the week
Humidity to home heroics: five things to look out for at the Rugby World Cup | Ben Ryan
Joe Marler gives England a scare after playing a limited part in training
Rugby World Cup 2019: Guardian writers’ predictions
Rugby World Cup shocks and routs, Solheim Cup drama and Ansu Fati | Classic YouTube
‘The pressure is on Japan’: Russia seek upset in Rugby World Cup opener
‘We’re not young any more’: Harry Kane angry Spurs are making same mistakes
Kieran Trippier delivering for Atlético Madrid and relishing new 100mph life
Southampton’s Jan Bednarek: ‘We have to be a really nasty opponent’
Astana sense 'great chance' of upset after their long road to Old Trafford
Roma's Nicolò Zaniolo: 'I’m not Totti, but one day I hope to be as good'
Stephen Colbert and Seth Meyers take a closer look at Elizabeth Warren's surge in the polls
Hustlers review – J-Lo's stealing strippers saga is a vicarious thrill
Céline Dion Just Wants To Be Hugged: 'I Miss What A Husband Would Do'
Instagram Cracks Down On Diet And Cosmetic Surgery Posts
Vegan? Here's Why You Might Not Want A Slice Of Lemon In Your Drink
Ralph Lauren's Friends Collection Celebrates Rachel Green
Alec Baldwin And Wife Hilaria Expecting Fifth Child, Five Months After Miscarriage
The Chase Star Paul Sinha Says He Had 'Breakdown' Shortly After Parkinsons' Diagnosis
John Humphrys Retires From The Today Programme – Here Are His Highlights And Controversies
CNN Analyst Condemns Whistleblower Complaint: Intel Community Should Not ‘Snitch’ on Trump to Congress
South Korea police say they may have found serial killer
Russia detains shaman on mission to 'banish Putin'
Man says church members pinned him down, tried to pray his homosexuality away
Anton Corbijn's unseen portraits of Arcade Fire – in pictures
The Breakdown | New Zealand have been fallible in World Cup years before – and won
For decadent, deficient Real Madrid the problems start in midfield | Jonathan Wilson
County cricket: Yorkshire v Kent, Lancashire v Middlesex – live!
'He became our best friend': how we survived Larry Nassar's systematic abuse
Trump's whistleblower-flagged 'promise' might have been to Putin, Washington Post reporters tell MSNBC
Hannity and Ingraham skip the pleasantries following Tuesday's awkward exchange
How Hustlers shows the importance of female solidarity
Bollywood film awards: Kashmiri spy thriller Raazi wins best picture
Kevin Spacey Accuser Dies, Leaving Future Of Sexual Assault Case Unclear
Digital Parents: How Connectivity Has Improved The Way We Bring Up Children
Taylor Swift Calls Out 'Two-Faced' Kanye West Over That Infamous Phone Call
I'm A Black Woman Who Gave End Of Life Care To A Ku Klux Klansman. This Is What It Taught Me
Demand For Food Banks Soars In Areas The Longer Universal Credit Exists, New Analysis Reveals
John Humphrys ends Today career with swipe at Corbyn and Johnson
Taliban open to new talks with US after bloody attacks
Costly Saudi defenses prove no match for drones, cruise missiles
Yemen rebels threaten strikes against Dubai and Abu Dhabi
'It's one big earworm': readers' picks of the best albums this century
Steve Hansen points finger at Rassie Erasmus for 'putting pressure on referees'
France confident of pipping England to top spot and going all the way to World Cup final
Stephen Colbert explains how Trump chose John Bolton's successor: Looks, flattery, A$AP Rocky. He wasn't joking
Nearly Half Of Working Renters 'One Pay Cheque Away From Losing Home'
Reebok Launches Maternity Fitness Collection Designed To Fit Every Stage Of Pregnancy
BBC 'ignoring its audience' over iPlayer app removal
The 'paradox' of John Humphrys: rottweiler, dinosaur or shy walker?
Television workers twice as likely to have attended private school
BBC apologises to Prince Harry over ‘race traitor’ image
Netanyahu's rule threatened by deadlocked Israeli polls
Filipino coast guard men convicted in Taiwan fisherman death
Exclusive: Pence rebuffs Solomon Islands PM after nation cuts ties with Taiwan
Mexico's Interjet grounds 2 workers after 'bomb' comment
Wales focus returns to pitch with brutal training session before Georgia match
I Didn't Lose Friends After Having Kids. I Just Moved On
How Dare David Cameron Pipe Up About Brexit Just To Sell His Memoirs?
Eco-Anxiety Is On The Rise. Here's What You Need To Know
Ghostly 'Drowning In Plastic' Photos Will Inspire You To Do Your Bit For The Environment
Gun victim Scalise leads opposition to stricter US laws
Trump to bar California from setting vehicle emission rules: sources
U.S. senators urge Trump administration to end nuclear talks with Saudis
Netanyahu, rightist allies appear to fall short of majority
French woman 'killed by partner in front of their three children'
Trump slaps new sanctions on Iran as Saudi Arabia displays missile debris as 'proof' Tehran backed oil attacks
Richie Mo’unga keeps All Blacks' flyhalf jersey for Springboks opener
Wallabies go with Pocock-Hooper combination for World Cup opener
Australia complete clean sweep with third T20 win in West Indies
Dustin Martin comes of age but crocodilian menace remains | Jonathan Horn
Send in the crowns: in trumping Venice competition, Joker begins grand slam | Xan Brooks
Close